Characterizing the assembly behaviors of human amylin: a perspective derived from C-terminal variants.
نویسندگان
چکیده
The differences in the C-terminal domains of human amylin peptide variants initiate different aggregation processes and differences in the composition of the aggregates by affecting the hydrophobic cores, conformations, and intra-sheet interactions of the peptides, which have distinct effects on the cytotoxicity of the peptides.
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عنوان ژورنال:
- Chemical communications
دوره 49 18 شماره
صفحات -
تاریخ انتشار 2013